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Image Search Results
Figure S11 . " width="100%" height="100%">
Journal: Molecular Therapy. Methods & Clinical Development
Article Title: Systemic Treatment of Fabry Disease Using a Novel AAV9 Vector Expressing α-Galactosidase A
doi: 10.1016/j.omtm.2020.10.016
Figure Lengend Snippet: Gb3 Deposits Are Reduced in Tissues from Adult Hemizygous Mice Injected at 3 Months of Age with scAAV9-PGK-GLA Representative immunofluorescence images of Gb3 deposit in tissues from hemizygous FD mice injected with two doses of scAAV9-PGK-GLA at the age of 3 month and their age-matched, noninjected controls. Mice were sacrificed 5 months after injection. Gb3 was detected with a CD77-fluorescein isothiocyanate (FITC) antibody (green), polymerized actin was stained with phalloidin-rhodamine (red), and nuclei were stained with DAPI (4',6-diamidino-2-phenylindol,blue). (A and B) Peripheral organs (liver, heart, and kidney) (A) andspinal cord, a dorsal root ganglion, and the spinal bone (B) . In heart and ganglion, scale bars, 50 μm; in the remaining images, scale bars, 75 μm. Mean fluorescence in the green channel (mean pixel intensity) was computed in different regions of interest for each image, and it is shown in
Article Snippet: Distribution of affected lysosomes was examined by Gb3 immunostaining with
Techniques: Injection, Immunofluorescence, Staining, Fluorescence
Journal: Cell Genomics
Article Title: Multi-omics integration identifies cell-state-specific repression by PBRM1-PIAS1 cooperation
doi: 10.1016/j.xgen.2023.100471
Figure Lengend Snippet:
Article Snippet: Primary antibodies used for western blotting include
Techniques: Recombinant, SYBR Green Assay, Protease Inhibitor, In Situ, Blocking Assay, Isolation, Sequencing, shRNA, Software